WebJul 30, 2024 · July 30, 2024 12:14 AM UTC Yale School of Medicine scientists including Aztek Bio Inc. co-founders Kingson Lin, Ranjit Bindra and Seth Herzon revealed in Science compounds that target drug-resistant gliomas. Most glioma tumors lack the methyl transferase MGMT and initially respond to the DNA methylation agent temozolomide. WebSep 2024 - Apr 20242 years 8 months New Haven County, Connecticut, United States Designed, synthesized and evaluated novel therapeutic agents for brain cancer as a graduate student in the...
New Class of Molecules Discovered by Bindra–Herzon …
WebJul 7, 2024 · MGMT silencing occurs at an even greater frequency in grade II and III gliomas (more than 70% of cases), and these tumors are also largely incurable (13). … WebApr 13, 2024 · Kingson Lin While at the University of Pennsylvania (UPenn)—where he received a BA in biochemistry and an MS in organic chemistry—Lin deepened his passion for chemistry and performed pioneering research in the laboratory of Professor Gary Molander. He also became an avid tutor and mentor. flooding in hemmant
Mechanism-based design of agents that selectively target …
WebApr 13, 2024 · His research has led to the discovery of a novel chemotherapeutic agent for drug resistant brain cancer. Lin has since co-founded a company with his research advisers at Yale to bring these new drugs to the clinic. WebPublications. Note: PDFs are provided for personal use only. 22. M Reschke, AS Piotrowski-Daspit, JS Pober, WM Saltzman: Nucleic acid delivery to the vascular endothelium. Molecular Pharmaceutics, in press, 2024. [ PDF] 21. AS Piotrowski-Daspit, C Barone, CY Lin, Y Deng, D Wu, AS Ricciardi, R Putman, R Nguyen, A Gupta, R Fan, PM Glazer, WM ... Web#NEWS: We emerged from stealth today with the announcement of our paper in Science Magazine. Congratulations to Modifi Bio co-founders Ranjit Bindra MD PhD, Seth … great marlborough estates chiswick