WebAuthor(s): Merski, Matthew; Shoichet, Brian K Abstract: Synthetic cavitands and protein cavities have been widely studied as models for ligand recognition. Here we investigate the Met102 → His substitution in the artificial L99A cavity in T4 lysozyme as a Kemp eliminase. Web9:30 Brian Shoichet (UCSF) 10:15 Minoru Yoshida (Tokyo, RIKEN) 10:35 Daniel Nomura (UC Berkley) 11:20 Kaori Sakurai (TUAT) 11:40 Break 11:50 Innovation Showcase (6 Talks from Startup Companies) 12:50 Lunch Break 14:30 Poster Session 16:00 Sean Cutler (UC Riverside) 16:45 Hirokazu Kawagishi (Shizuoka) ...
Shoichet Lab : Publications
WebFeb 12, 2024 · This was only possible thanks to the chemical novelty afforded by an ultra-large virtual library of synthesizable compounds,” said Brian Shoichet, PhD, professor of pharmaceutical chemistry in UCSF’s School of Pharmacy and … WebAuthor(s): Kruse, Andrew C; Weiss, Dahlia R; Rossi, Mario; Hu, Jianxin; Hu, Kelly; Eitel, Katrin; Gmeiner, Peter; Wess, Jürgen; Kobilka, Brian K; Shoichet, Brian K Abstract: G protein-coupled receptors (GPCRs) regulate virtually all aspects of human physiology and represent an important class of therapeutic drug targets. Many GPCR-targeted drugs … cooch behar lok sabha
Faculty Honors and Awards · PhD Degree Program in ... - UCSF
WebThe Shoichet lab seeks to discover chemical reagents that can illuminate biological problems. A longstanding effort to do so is by exploiting protein structures to predict new … WebBrian Shoichet, UCSF Established scientists, especially academics, are regularly asked to review papers. Doing so twice a month is common, and a rule of thumb is that for every … WebSep 30, 2024 · “We showed that it’s possible to separate the analgesic and sedative effects related to this receptor,” said Brian Shoichet, PhD, professor in the School of Pharmacy, and one of four senior authors of the study, which appears in the Sept. 30, 2024 issue of Science. “That makes it a very promising target for drug development.” cooch behar nearest airport