Phospho eif4b

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August undefined, 2024

WebAnti-eIF4B (phospho S422) antibody See all eIF4B primary antibodies Description Rabbit polyclonal to eIF4B (phospho S422) Host species Rabbit Tested applications Suitable for: … WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins …

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WebPhospho-EIF4B-S422 Rabbit pAb (AP0775) Datasheet SDS Tested applications: WB Reactivity: Human Western blot analysis of extracts of HeLa cells, using Phospho-EIF4B-S422 antibody (AP0775) at 1:2000 dilution. HeLa cells were treated by EGF (100ng/mL) for 30 minutes after serum-starvation overnight. WebJun 8, 2024 · The phosphorylation of eIF2α occurs on serine 51 in response to the activation of one out of four eIF2α kinases 4, 5, 6. EIF2AK1, commonly known as heme-regulated inhibitor (HRI), is activated by... greenies snowman dog commercial

Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) - Abcam

WebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using phospho-EIF4B-S422 antibody (AP0278). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and … WebJan 5, 2024 · The translation initiation factor eIF4A is a member of the “DEAD box” family of helicases that catalyze the ATP-dependent unwinding of RNA duplexes and facilitates 43S ribosome complex scanning through highly structured regions of the 5′-untranslated region (UTR) and recognition of the AUG initiation codon. flyer bracer suspension 27.2 x 300 mm

Anti-eIF4B (phospho S422) antibody (ab59300) Abcam

WebHuman Phospho-eIF4B (S422) Antibody Summary Species Reactivity Human Specificity Detects human eIF4B when phosphorylated at S422 Source Monoclonal Rat IgG 2A Clone # 866049 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing the human eIF4B S422 site Formulation WebAug 4, 2024 · Phosphorylated eIF4B levels are normalized against total eIF4B, then for loading (Tubulin) and shown as fold change over control (untreated neurons). Data are … greenies subscriptionWebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors such as eIF4B through the depletion of the ATP supply, which resulted in a critical reduction of p-eIF4B dependent synthesis of proteins including c-Myc in cancer cells (Fig. 4 b). flyer brochure crossword

"WebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using … " - Phospho eif4b

Phospho eif4b

Loss of SLC25A11 causes suppression of NSCLC and melanoma …

WebInvitrogen Anti-Phospho-EIF4B (Ser504) Polyclonal, Catalog # PA5-114571. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (PFA fixed) … WebPhospho-eIF4B (Ser406) Antibody detects endogenous levels of eIF4B protein only when phosphorylated at Ser406. Species Reactivity: Human, Mouse. Species predicted to react …

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WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. WebNov 18, 2016 · The activity of eIF4B is modulated by phosphorylation, which is mediated by two major signaling pathways, the MEK1/2-ERK1/2-RSK pathway and the PI3K-Akt-mTORC1-S6K pathway [8], [9], [11], [12]. Overexpression or depletion of eIF4B affects cell survival and proliferation [13], [14].

WebEIF4B Antibody (phospho-Ser422) LS-C826726 Antibody: EIF4B Rabbit anti-Human Polyclonal (pSer422) Antibody . Reactivity: Mouse, Rat, Human . Applications: ELISA, IF, IHC, WB . Format: Unconjugated . Price: 1 mg/$357. Select. EIF4B Antibody LS-C334046 Antibody: EIF4B Rabbit anti-Human Polyclonal Antibody ... WebWestern blot analysis of extracts from HeLa cells, untransfected or transfected with SignalSilence ® eIF4B siRNA #6416, using Phospho-eIF4B (Ser422) Antibody (upper) or eIF4B Antibody #3592 (lower). 48 hours following transfection, cells were treated with Rapamycin (50 nM) and U0126 (10 uM) as indicated.

WebOct 6, 2008 · Insulin stimulation resulted in phosphorylation of eIF4B as detected by both the phospho-eIF4B Ser422 antibody as well as the phospho-PKB substrate antibody (Figure 5a, lanes 1 and 2). WebAnti-eIF4B (phospho S422) antibody See all eIF4B primary antibodies Description Rabbit polyclonal to eIF4B (phospho S422) Host species Rabbit Tested applications Suitable for: IHC-P, WB, ICC/IF more details Species reactivity Reacts with: Mouse, Human Immunogen Synthetic peptide corresponding to Human eIF4B aa 350-450 (phospho S422). T-G-SP-E-S

WebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP …

WebJun 8, 2006 · eIF4B Ser422 phosphorylation persists in cells lacking S6K1 and S6K2 To further corroborate the existence of an eIF4B kinase that is distinct from S6K in cells … flyer brocanteWebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. flyer brochureWebSep 5, 2024 · eIF4B phosphorylation patterns in hippocampal neurons and cortical astrocytes. ( A) Western blot analysis of total cell extracts from neurons or astrocytes … flyer box home depotPolyclonal Antibody for studying eIF4B (Ser422) phosphate. Cited in 46 publications. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-eIF4B (Ser422) Antibody (CST #3591) is ready to ship. greenies soft snacks for catsWebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. greenies sports card showWebRecombinant Recombinant Anti-eIF4B (phospho S406) antibody [EPR7683] (ab134138) Datasheet SDS Submit a review Submit a question References (2) Key features and details Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR7683] to eIF4B (phospho S406) Suitable for: … greenies sports cardsWebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth … greenies smartbite hairball tuna cat treat