WebNov 12, 2024 · When it comes to programmed cell death (PCD), apoptosis is usually the first process that comes to mind. However, there is a new type of inflammatory PCD … WebFeb 12, 2024 · Ferroptosis is an intracellular iron-dependent form of cell death that is distinct from apoptosis, necrosis, and autophagy. Extensive studies suggest that ferroptosis plays a pivotal role in tumor suppression, thus providing new opportunities for cancer therapy. The development of resistance to cancer therapy remains a major challenge.

Recent progress in ferroptosis: inducers and inhibitors

WebTargeting the cell death process is a common approach in cancer therapy, and ferroptosis, a new form of programmed cell death, is also thought to play an important role in anti-cancer treatment. Ferroptosis, a hot topic of research in recent years, has been gradually enriched by its corresponding regulatory mechanisms. WebTargeting the cell death process is a common approach in cancer therapy, and ferroptosis, a new form of programmed cell death, is also thought to play an important role in anti … eve online c3 wormhole guide

Ferroptosis: past, present and future Cell Death & Disease

It has been found that ferroptosis inhibitors can effectively repair I/R-induced cell damage. Gao et al.25 found that inhibiting ferroptosis by inhibiting glutamine … See more In 2014, two articles mentioned studies of kidney damage in mice, the first involving ferroptosis in a mouse model. In GPX4 knockout mice, the incidence and mortality in spontaneous AKI increased significantly76. In … See more Studies have shown that ferroptosis is closely related to the pathophysiological processes of more and more diseases. For example, ART treatment can significantly reduce the degree of liver injury and inhibit the formation of … See more WebFerroptosis is a newly defined programmed cell death process with the hallmark of the accumulation of iron-dependent lipid peroxides. The term was first coined in 2012 by the Stockwell Lab, who described a unique type of cell death induced by the small molecules erastin or RSL3. WebMar 15, 2024 · Background: Cardiovascular disease (CVD) remains the leading cause of disease burden worldwide. Ferroptosis, an iron-dependent form of programmed cell death, is characterized by the lethal accumulation of lipid peroxidation, which is morphologically, biochemically, and genetically distinct from apoptosis, necrosis, and pyroptosis. Emerging … brother xr9000 accessories